Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis.
Low Impact Exercise Reduces Fatigue in Adults with Autoimmune Conditions such as MS, Rheumatoid Arthritis, Lupus
A systematic review of the literature reveals that low impact aerobic exercise, gradually increasing in intensity, duration & frequency, reduces fatigue in people with auto-immune conditions.
Researchers from Flinders University in Adelaide, Australia did a systematic review of non-pharmacological interventions for fatigue in adults with three common autoimmune conditions: M.S., rheumatoid arthritis and lupus. The literature search included 19 electronic databases and libraries, three evidence-based journals and two internet search engines, from 1987-2006, and limited to English.Thirty-three primary studies reported 14 randomized controlled trials and 19 quasi-experimental designs. Most interventions were tested with people with multiple sclerosis. Exercise, behavioral, nutritional and physiological interventions were associated with statistically significant reductions in fatigue.
Although the diversity of interventions, designs, and instruments limited comparisons, the study did find that low impact aerobic exercise, gradually increasing in intensity, duration and frequency, may be an effective strategy in reducing fatigue in some adults with chronic auto-immune conditions. Electromagnetic field devices showed promise.
The authors recommend well-designed studies testing these promising strategies and that there be consensus on outcome fatigue measures.
Citation: Neill J, Belan I, Ried K. Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis, rheumatoid arthritis, or systemic lupus erythematosus: a systematic review. Journal of Advanced Nursing. 2006 Dec; 56 (6): pages 617-35. [email protected].