Investigators from the Clinique du Mail in La Rochelle, France, conducted a randomized, prospective, controlled study, comparing the efficacy of hypnosis on patients receiving embryo transfer, to measure impact on pregnancy rates and degree of anxiety, as compared to the efficacy of Diazepam (Valium).
Previous research by Levitas et al (2006) showed in a cohort study that hypnosis during embryo transfer (ET) increased the pregnancy ratio by 76%.
In order to evaluate hypnosis during ET in a general population, the authors compared the impact of diazepam (usual premedication) administered before ET plus muscle relaxation, versus hypnosis plus placebo, in 94 patients.

Additionally, the authors studied anxiety pre and post ET. Anxiety scores were not different in the two groups before and after ET. No difference in pregnancy and birth ratio was found in the two groups.

The researchers conclude that hypnosis during ET is as effective as diazepam in terms of pregnancy ratio and anxiety, but with fewer side effects. They recommend that hypnosis be routinely available.

Citation:  Catoire P, Delaunay L, Dannappel T, Baracchini D, Marcadet-Fredet S, Moreau O, Pacaud L, Przyrowski D, Marret E. Hypnosis versus diazepam for embryo transfer: a randomized controlled study. American Journal of Clinical Hypnosis. 2013 Apr; 55 (4): pages 378-86. [email protected]